MBIO 687

Microbial Pathogenesis

A detailed discussion of host-parasite interactions, focusing on the characteristics (i.e., virulence factors) of bacteria that enable them to cause disease. Exotoxins, capsules, adherence mechanisms, intracellular replication, and iron metabolism will be described in detail. Specific bacterial diseases will be examined to illustrate how each virulence factor is required in the infectious process. The use of animals and other model systems will be discussed. Graded. Spring

Units: 2.0