Seminole State College of Florida is a public state college with four campuses in Central Florida, United States. Seminole State is the eighth-largest member institution of the Florida College System.

Founded in 1965, the Florida State Legislature signed a charter creating "Seminole Junior College." The college opened in August 1966 with 700 students at a former citrus grove in Seminole County, near U.S. Route 17/92 and County Road 427 (Ronald Reagan Blvd.) now in the city of Sanford. By October 1971, Seminole Junior College's enrollment had exceeded 7,000, and by 1975, Seminole Junior College became "Seminole Community College", with enrollment reaching 14,161. In 2006, Seminole Community College partnered with the University of Central Florida to launch "DirectConnect to UCF", which guaranteed Seminole Community College graduates admission to the university, as well as academic advising by university counselors. In September 2009, the college's board of trustees unanimously approved a motion to rename the institution "Seminole State College of Florida," eight months after the introduction of the institution's first state-approved bachelor's degree program, the Bachelor of Applied Science (B.A.S.) in interior design.